I don't like this scenario because there are no guarantees in the draft.
But even with a guarantee that Nelson would be Martin, I still need to know my grades on the rest of the prospects. Who's still on the board, and how do I view them? If I have a similar grade on Chubb, for instance, I'm going with Chubb. If my phone is ringing off the hook and I can add nice picks and stay in the top 6-8, I'm probably going to trade down, especially if I think whoever is calling me wants one of the QBs. There's recent chatter -- and it's lying season, so it might not matter -- that Josh Allen and Baker Mayfield might go top 5-ish. The third pick might be super hot.
My first step is to evaluate everyone honestly. My last step, before I do anything with the pick, is to feel confident that I'm getting the most value out of the pick as I can. I don't think taking a guard is going to represent the best value, when all is said and done.
So, short answer probably not.
By the way, the last two guards to go top ten were Jonathan Cooper and Chance Warmack, two guys who were presumed to be 'can't miss' interior OL prospects, the next whoever. Cooper certainly hasn't performed to that level, and Warmack has been decent, but not worthy of the #10 pick that was used on him (Kyle Long went at #20, and he's been better). Lots of these 'can't miss' guys wind up missing. Scout honestly.