According the football ''experts'' everywhere, the Colts do not stand a chance against the 49ers.
This is what NFL.com picks:
The San Francisco 49ers will bounce back in a major way, thwarting an Indianapolis Colts offense that will need to run the football but will have a hard time doing so, even with Trent Richardson. Ahmad Bradshaw ran for 116 yards the last time he played at the 'Stick, but that was last year, and that was for the New York Giants. Richardson, meanwhile, is too new to be expected to get his playbook, learn the offense and rack up 100 yards on the 49ers' defense. On the passing front, Indy must protect Andrew Luck by leaving a tight end in sometimes; don't forget that Dwayne Allen is out for the year. The key for Indy might be the matchup between Reggie Wayne and Niners cornerback Carlos Rogers when the veteran Colts receiver plays out of the slot. As far as the Niners' offense is concerned, we can expect Frank Gore to get 20-25 touches following a rough night in Seattle (nine carries for 16 yards) last Sunday. I don't expect San Francisco's offensive line to have trouble with Indianapolis' defensive front.
This is what ESPN predicts (All 49ers): http://espn.go.com/nfl/picks
This is what USA Today predicts: http://www.usatoday.com/story/sports/nfl/2013/09/19/staff-picks-week-3-predictions/2836643/
This is what Sports Illustrated Picks:
4:25 p.m. ET (CBS) Indianapolis Colts (1-1) at San Francisco 49ers (1-1)
Don't ever remember seeing Jim Harbaugh wear glasses on the sideline like he did last Sunday night in Seattle. It was almost as if the 49ers' head coach couldn't believe his eyes, given the whipping the bad-butt Seahawks were administering to his talented and well-balanced team. San Francisco was probably in a foul mood this week with wounded pride, and that means the Colts could suffer the consequences. Welcome back to the Bay Area, Andrew Luck. Now kindly prepare for defeat, signed, the 49ers.
After searching and searching I found a pick from SB Nation that believes in us:
Indianapolis Colts vs. San Francisco 49ers (-10)
Jim Harbaugh reunited with his former quarterback at Stanford. Somehow I suspect Harbaugh in hyper-focused coach mode has as much sentimentality about the reunion as the rest of the world does. After all, it's not like he had much time or interest in a reunion with Richard Sherman last week, another one of his former players. On the Colts' side, it doesn't sound like Trent Richardson will be ready for a full-time role this week. This is another one of those giant spreads, which I've been warning you about. The 49ers should win this one outright, but I'm picking the Colts to cover.
The pick: Indianapolis
Then I went to CBS.com to see what they picked:
IND at SF Sep 22, 4:25 PM ET -10.5
So what does all these picks really mean, nothing, but it is interesting on how people feel about the Colts. Only five people are in favor of the Colts versus all of the people that are in favor of the 49ers. This will be a tough game and the majority is probably right, but they don't give the Colts much of a chance do they. We beat the Packers after coming off a loss from the Jaguars. Who's to say we won't beat the 49ers coming off a loss to the Dolphins.