We are usually winning TOP by a solid margin. If the opposing D is getting tired there's more chance for injuries. Our D is getting pressure that leads to QB injuries. Fuller is just a bit injury prone.
The Colts are playing physical...but I would venture to guess that the turf has more impact than the Colts style of play. It's not like it's concussions, contusions, cracked ribs, broken bones, etc...all of those guys have groin and leg issues I think.