He'd be fun to have. Gives the O options. Run him, use him in the slot. Can probably draw some trick plays too with him in mind.
But the team needs an every down running back. One they can rely on to carry the load if need be. Granted, on Indy's offense, the passing attack is always the number 1 threat, but they still need a guy to carry it 15 + times a game to keep defenses honest. I don't think Samuel can be that guy. So whilst having him would be cool, it's not essential to this O and certainly not the best way to Colts can spend a third round pick.
By the way, and I might be wrong, but isn't he getting 2nd round grades by a lot of people right now? I'll have to check again but I'm pretty sure he is.
You know I agree, but to play devils advocate to my own opinion, I could see McDaniels being the one guy he would make a change for. (Or Shanahan, but he's headed to SF from what the reports say, so I left him out.)
Even still, I'd have to wager there is less than a 10% chance it happens. Maybe even less than 5.