Buffalo and Indianapolis have met 66 times previously, largely on the basis of being paired in the AFC East from 1970-2001. This marks only the fourth series renewal since 2002 divisional realignment, and this is the first regular-season visit by Buffalo to Lucas Oil Stadium. The Bills lead the series, 35-30-1. The Colts have won 12-of-19 meetings in Indianapolis, and they hope to move to 7-4 with a win Sunday over a former divisional foe.
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