It does make a difference because you'd said that there were exactly one first round on the line when in actual fact there are two.
I agree that Luck gets hit too much however the quarterbacks that get hit less don't necessarily need their whole line made up of 1st, 2nd and 3rd round picks. Same goes for running back who rush more successfully that Gore. I believe that once you have some talented guys on the line that you should be able to fill the remaining gaps creatively by finding effective role players, coaching and scheme.
Taking another OL at 15 is too much for me. I don't know if there's ever been a successful team whose line was chosen 22-59-18-15-82. It shows a lack of creativity in an area where successful teams plug and play low round picks and undrafted guys.
Losing yet another opportunity to improve our defense and taking the option to invest in an area which could be improved without spending significant resource is a complete waste of an opportunity.