It would be the worst thing for THIS year, but certainly not for down the road. Of course, we have no idea what will happen this season, let alone in 2-3 years. Who knows if Andy's shoulder ever fully heals? If that happens, he won't even be in Indy and they will have moved onto someone else. So I think if he can go, you put all your chips on the table to try to win this season. If he can't, you hold him out, go 5-11 or whatever, draft well, make some more splashes in FA with all the money they are projected to have, and then hope 2018 lines up better.
This whole thing hinges on Andrew really. And until we know more about his health all things Colts are sort of up in the air for this season.